tag:blogger.com,1999:blog-8550428.post572065484563172835..comments2024-03-28T13:38:36.788-04:00Comments on Pharma Marketing Blog: Crestor Print Ad Touts Plaque Buildup AdvantageVladhttp://www.blogger.com/profile/04114063498108633047noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-8550428.post-81835269542181343832008-01-30T20:03:00.000-05:002008-01-30T20:03:00.000-05:00John, I thought you might find this interesting. ...John, I thought you might find this interesting. Brandweeknrx.com has found cafepharma postings that indicate SP employees new about the results of ENHANCE as early as March 13, 2007. This would be only a few weeks before Carrie Cox sold her stock. It also strongly hitns at why MSP pulled the ENHANCE results from the ACC at about the same time.<BR/>http://www.brandweeknrx.comAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-8550428.post-12572325639305344422008-01-29T17:08:00.000-05:002008-01-29T17:08:00.000-05:00Crestor actually reversed athersclerotic plaque in...Crestor actually reversed athersclerotic plaque in the coronary arteries (as measured by IVUS) in the Asteroid study. Crestor still doesn't have an indication to do that, but the results were impressive. As for the number of patients in Meteor, a study either yields statistically significant results or it does not. Meteor did. The <BR/>ENHANCE study was more than sufficiently powered (with around 700 patients) to yield statistically significant results in a surrogate marker type study. As for ENHANCE's patient population, the heterozygousfamilial hypercholesterolemic pateint population grows plaque quicker than any other group. That's why MSP selected this type of patient. The 17% LDL spread should have produced some difference in plaque progression. We learned from torcetrapib that it wasn't just raising HDL, but how you raise HDL that apparently makes a difference. Perhaps ENHANCE has taught us that how you lower LDL makes a difference too. Regardless of what you think of the study or Zetia, MSP's behavior has been inexcusable throughout this entire ordeal. Regarding head to head Studies, Prove-It, IDEAL, and ENHANCE may have Pharmaceutical companies thinking twice before they do their next head to head trial..lol Can't wait to see the SATURN (Lipitor vs. Crestor) results...lol If the pattern of the company setting up the study losing continues, AZ better watch out!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8550428.post-11702851708716237762008-01-29T16:36:00.000-05:002008-01-29T16:36:00.000-05:00Thanks. I meant to say Zocor, not Mevacor -- corre...Thanks. I meant to say Zocor, not Mevacor -- correction made.PharmaGuyhttps://www.blogger.com/profile/10211557578124130640noreply@blogger.comtag:blogger.com,1999:blog-8550428.post-83220631787147466322008-01-29T16:31:00.000-05:002008-01-29T16:31:00.000-05:00Simvastatin is generic Zocor. Lovastatin is gener...Simvastatin is generic Zocor. Lovastatin is generic Mevecor.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8550428.post-72947734959344425462008-01-29T10:49:00.000-05:002008-01-29T10:49:00.000-05:00Love it John!The irony is perfect.Love it John!<BR/><BR/>The irony is perfect.insiderhttps://www.blogger.com/profile/16046281532123990259noreply@blogger.com